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Neuro ResearchSelank
Synthetic tuftsin analog with glyproline extension, studied for anxiolytic-like effects and cognitive function in research models.
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Product information
CompoundSelank
Presentation10mg vial
CategoryNeuro Research
AvailabilityIn stock
Batch COACertificate supplied with order
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For research use only. Not for human consumption, diagnostic, therapeutic or veterinary use.
Overview
Selank (TP-7) is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It consists of the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg) extended with a C-terminal glyproline sequence (Pro-Gly-Pro) that confers enzymatic stability. Selank was approved as an anxiolytic medication in Russia in 2009 and has been the subject of extensive neuroscience research. Unlike benzodiazepines, it does not produce sedation, tolerance, or withdrawal effects in the models studied.
Mechanism of Action
Selank modulates the balance of monoamine neurotransmitter metabolism — increasing serotonin (5-HT) levels while stabilising norepinephrine degradation rates. It enhances the expression of BDNF (brain-derived neurotrophic factor) in the hippocampus, promoting neuroplasticity. Selank also influences the GABAergic system, acting as an allosteric modulator that enhances GABA-A receptor sensitivity without directly binding the benzodiazepine site. Its immunomodulatory effects, inherited from tuftsin, include modulation of IL-6, TNF-α, and other cytokines.
Research Applications
- Anxiolytic mechanism research without sedative interference
- BDNF-mediated neuroplasticity studies
- Monoamine metabolism and serotonin pathway research
- Neuroimmune interaction and cytokine modulation
- Cognitive function and memory consolidation models
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Reconstitution calculator
Enter your reconstitution to get the draw volume for Selank.
Concentration5.00 mg/ml
Draw volume0.050 ml
On the syringe5.0 units
Doses per vial40
5units
Pull the plunger to 5.0 units on a 1 ml U‑100 syringe0.050 ml · 5.00 mg/ml · 40 doses per vial
Concentration = peptide mass ÷ water volume. Unit readings assume U-100 insulin syringes, graduated 100 units per millilitre. For laboratory calculation only — not dosing guidance.